Dimaprit dihydrochloride

Name: Dimaprit dihydrochloride
Brand: Tocris Bioscience
SKU: 0506

Cat. No. 0506 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0506 has been discontinued.

View all Histamine H<sub>2</sub> Receptors products.

说明： Standard H₂ selective agonist

化学名： S-(3-Dimethylaminopropyl)isothiourea dihydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献 (3)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Dimaprit dihydrochloride

Dimaprit dihydrochloride is a selective H₂ agonist with central effects upon systemic administration. Also inhibits nNOS (IC₅₀ = 49 μM).

技术数据 for Dimaprit dihydrochloride

分子量	234.19
公式	C₆H₁₅N₃S.2HCl
储存	Desiccate at RT
纯度	≥99% (HPLC)
CAS Number	23256-33-9
PubChem ID	90045
InChI Key	DFWCPLGXFMSUCW-UHFFFAOYSA-N
Smiles	CN(C)CCCSC(N)=N.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Dimaprit dihydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Dimaprit dihydrochloride

参考文献是支持产品生物活性的出版物。

Durant et al (1977) Dimaprit-(S-[3-(N,N-dimethylamino)propyl]isothiourea) a highly specific histamine H₂-receptor agonist. Part 2. Structure activity considerations. Agents Actions 7 39 PMID: 860674

Farzin and Attarzadeh (2000) Influence of different histamine receptor agonists and antagonists on apomorphine-induced licking behavior in rats. Eur.J.Pharmacol. 404 169 PMID: 10980276

Paquay et al (1999) Nitric oxide synthase inhibition by dimaprit and dimaprit analogues. Br.J.Pharmacol. 127 331 PMID: 10385230

Parsons et al (1977) Dimaprit-(S-[3-(N,N-dimethylamino)propyl]isothiourea)-a highly specific histamine H₂-receptor agonist. Part 1. Pharmacology. Agents Actions 7 31 PMID: 871093

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关键词: Dimaprit dihydrochloride, Dimaprit dihydrochloride supplier, H2, selective, agonists, Receptors, Histamine, histaminergic, 0506, Tocris Bioscience

3 篇 Dimaprit dihydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Dimaprit dihydrochloride 的部分引用包括：

Swartzendruber et al (2012) Cutting edge: histamine is required for IL-4-driven eosinophilic allergic responses. Stem Cells Transl Med 188 536 PMID: 22156496

Wang et al (2014) Roles of histamine on the expression of aldehyde dehydrogenase 1 in endometrioid adenocarcinoma cell line. J Immunol 3 1126 PMID: 25045085

Fei et al (2009) Stimulation of mucosal secretion by lubipro. (SPI-0211) in guinea pig small intestine and colon. Am J Physiol Gastrointest Liver Physiol 296 G823 PMID: 19179625