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Submit ReviewDiprenorphine
说明： Non-selective opioid antagonist
化学名： 17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-6,14-ethenomorphinan-7-methanol
纯度： ≥99% (HPLC)
生物活性 for Diprenorphine
Diprenorphine is a non-selective opioid receptor antagonist (Ki values are 0.017, 0.072 and 0.23 nM for κ-, μ- and δ-opioid receptors).
技术数据 for Diprenorphine
| 分子量 | 425.56 |
| 公式 | C26H35NO4 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 14357-78-9 |
| PubChem ID | 443408 |
| InChI Key | OIJXLIIMXHRJJH-KNLIIKEYSA-N |
| Smiles | OC1=CC=C3C2=C1O[C@@H]([C@]7(OC)[C@@H]([C@@](C)(O)C)C4)[C@]52[C@@]4(CC7)[C@H](N(CC6CC6)CC5)C3 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Diprenorphine
参考文献 for Diprenorphine
参考文献是支持产品生物活性的出版物。
Paterson et al (1983) Classification of opioid receptors. Br.Med.Bull. 39 31 PMID: 6301606
Raynor et al (1994) Pharmacological characterization of the cloned κ-, δ-, and μ-opioid receptors. Mol.Pharmacol. 45 330 PMID: 8114680
Iwasaki et al (1994) The effect of the nonselective opioid antagonist diprenorphine vasopressin secretion in the rat. Endocrinology 134 48 PMID: 8275962
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关键词: Diprenorphine, Diprenorphine supplier, Non-Selective, opioids, antagonists, Receptors, Miscellaneous/Non-selective, Opioids, 2965, Tocris Bioscience
1 篇 Diprenorphine 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Diprenorphine 的部分引用包括：
Gardner et al (2015) Separating myoblast differentiation from muscle cell fusion using IGF-I and the p38 MAP kinase inhibitor SB202190. Am J Physiol Cell Physiol 309 C491 PMID: 26246429
Diprenorphine 的评论
平均评分: 5 (Based on 1 Review.)
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Diprenorphine in binding experiment.
By
Anonymous on 01/13/2020
分析类型： In Vitro
种属： Human
Diprenorphine was use to displace radiolabeled-diprenorphine in an homologous radiobinding assay.
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