Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review(±)-Nipecotic acid
说明： GABA uptake inhibitor
化学名： (±)-3-Piperidine carboxylic acid
生物活性 for (±)-Nipecotic acid
GABA uptake inhibitor. IC50 values are 8, 38, 106 and 2370 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
技术数据 for (±)-Nipecotic acid
| 分子量 | 129.16 |
| 公式 | C6H11NO2 |
| 储存 | Store at RT |
| CAS Number | 60252-41-7 |
| PubChem ID | 4498 |
| InChI Key | XJLSEXAGTJCILF-UHFFFAOYSA-N |
| Smiles | O=C(C1CNCCC1)O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for (±)-Nipecotic acid
分析证书目前不在网上提供。
请联系客户服务
请联系客户服务
参考文献 for (±)-Nipecotic acid
参考文献是支持产品生物活性的出版物。
Borden et al (1994) Tiagabine, SK&F 89976-A, CI 966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur.J.Pharmacol. 269 219 PMID: 7851497
Krogsgaard-Larsen et al (1981) GABA agonists, antagonists and uptake inhibitors. Design and therapeutic aspects. J.Med.Chem. 24 1377 PMID: 6118436
Schousboe et al (1979) Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA binding. J.Neurochem. 33 181 PMID: 458448
按产品操作查看相关产品
关键词: (±)-Nipecotic acid, (±)-Nipecotic acid supplier, GABA, reuptake, inhibitors, inhibits, BGT-1, GAT-1, GAT-2, GAT-3, GAT-4, Transporters, Monoamine, Neurotransmitter, 0236, Tocris Bioscience
1 篇 (±)-Nipecotic acid 的引用文献
引用文献是使用了 Tocris 产品的出版物。 (±)-Nipecotic acid 的部分引用包括：
Reali et al (2011) GABAergic signalling in a neurogenic niche of the turtle spinal cord. J Physiol 589 5633 PMID: 21911613
(±)-Nipecotic acid 的评论
目前没有该产品的评论。 Be the first to review (±)-Nipecotic acid and earn rewards!
Have you used (±)-Nipecotic acid?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.