(±)-Vesamicol hydrochloride

Name: (±)-Vesamicol hydrochloride
Brand: Tocris Bioscience
SKU: 0653

Cat. No. 0653 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0653 has been discontinued.

View all Acetylcholine Transporters products.

说明： Inhibits ACh transport

别名： AH 5183

化学名： (±)-trans-2-(4-Phenylpiperidinyl)cyclohexanol hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for (±)-Vesamicol hydrochloride

(±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (K_i = 2 nM). Centrally active following systemic administration in vivo.

技术数据 for (±)-Vesamicol hydrochloride

分子量	295.85
公式	C₁₇H₂₅NO.HCl
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	120447-62-3
PubChem ID	659839
InChI Key	XJNUHVMJVWOYCW-GBNZRNLASA-N
Smiles	O[C@@H]1CCCC[C@H]1N(CC3)CCC3C2=CC=CC=C2.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for (±)-Vesamicol hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for (±)-Vesamicol hydrochloride

参考文献是支持产品生物活性的出版物。

Efange et al (1997) N-hydroxyalkyl derivatives of 3β-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J.Med.Chem. 40 3905 PMID: 9397171

Kobayashi et al (1997) Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats. Brain Res.Bull. 43 17 PMID: 9205789

Varoqui and Erickson (1996) Active transport of acetylcholine by the human vesicular acetylcholine transporter. J.Biol.Chem. 271 27229 PMID: 8910293

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关键词: (±)-Vesamicol hydrochloride, (±)-Vesamicol hydrochloride supplier, AH5183, inhibitors, inhibits, ACh, transport, Acetylcholine, Transporters, Monoamine, Neurotransmitter, AH, 5183, 0653, Tocris Bioscience

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