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说明： LRH-1 agonist; regulates bile acid metabolism
化学名： (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide
生物活性 for DLPC
Selective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.
技术数据 for DLPC
| 分子量 | 621.83 |
| 公式 | C32H64NO8P |
| 储存 | Store at -20°C |
| CAS Number | 18194-25-7 |
| PubChem ID | 512874 |
| InChI Key | IJFVSSZAOYLHEE-SSEXGKCCSA-N |
| Smiles | [O-]P(OC[C@H](OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for DLPC
参考文献 for DLPC
参考文献是支持产品生物活性的出版物。
Lee et al (2011) A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature 474 506 PMID: 21614002
关键词: DLPC, DLPC supplier, Dilauroyl, phosphatidylcholine, LRH-1, agonist, orphan, nuclear, receptor, agonists, NR5A2, saturated, fatty, acid, chain, liver, homolog, homologue, Other, Nuclear, Receptors, Lipid, Metabolism, 4378, Tocris Bioscience
2 篇 DLPC 的引用文献
引用文献是使用了 Tocris 产品的出版物。 DLPC 的部分引用包括：
Zimmerlin et al (2016) Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality. Development 143 4368 PMID: 27660325
Zhu et al (2014) Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature 508 93 PMID: 24572354
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