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Discontinued Product
3428 has been discontinued.
说明： Endogenous σ1 ligand. Also 5-HT2A agonist
别名： Dimethyltryptamine
化学名： N,N-Dimethyl-1H-indole-3-ethanamine
纯度： ≥99% (HPLC)
生物活性 for DMT
Endogenous σ1 receptor ligand and psychoactive plant compound (Ki = 14.8 μM). Binding to σ1 inhibits voltage-gated Na+ channels and is responsible for the behavioral effects of DMT. Also a 5-HT2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (Ki = 4.0 μM).
技术数据 for DMT
| 分子量 | 188.27 |
| 公式 | C12H16N2 |
| 储存 | Store at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 61-50-7 |
| PubChem ID | 6089 |
| InChI Key | DMULVCHRPCFFGV-UHFFFAOYSA-N |
| Smiles | CN(CCC2=CNC1=CC=CC=C12)C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for DMT
参考文献 for DMT
参考文献是支持产品生物活性的出版物。
Fontanilla et al (2009) The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator. Science 323 934 PMID: 19213917
Cozzi et al (2009) Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transportere and the vesicle monoamine transporter. J.Neural Transm. 116 1591 PMID: 19756361
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关键词: DMT, DMT supplier, sigma, σ, sigma1, σ1, receptors, ligands, 5-HT2A, serotonin, agonists, SERT, transporters, 5-HT, N,N-Dimethyltryptamine, Sigma1, Receptors, Transporters, 3428, Tocris Bioscience
1 篇 DMT 的引用文献
引用文献是使用了 Tocris 产品的出版物。 DMT 的部分引用包括：
Do-Monte et al (2015) A temporal shift in the circuits mediating retrieval of fear memory. BMC Cancer 519 460 PMID: 25600268
DMT 的评论
平均评分: 5 (Based on 1 Review.)
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DMT protects sigma-1 receptor against photolabeling by iodoazidofenpropimorph.
By
Anonymous on 02/26/2018
分析类型： In Vitro
种属： Mouse
细胞系/组织： mouse spinal cord homogenate
Photolabeling experiment on mouse spinal cord homogenate
