Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewDomoic acid
说明： Potent and selective kainate agonist
化学名： (2S,3S,4R,5'R)-2-Carboxy-4-(5'-carboxy-1'-methyl-1Z,3E-hexadienyl)-3-pyrrolidineacetic acid
纯度： ≥95% (HPLC)
生物活性 for Domoic acid
Domoic acid is a kainate receptor agonist. More potent and possibly more selective than kainate at kainate receptors, as demonstrated in electrophysiological studies.
技术数据 for Domoic acid
| 分子量 | 311.33 |
| 公式 | C15H21NO6 |
| 储存 | Desiccate at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 14277-97-5 |
| PubChem ID | 5282253 |
| InChI Key | VZFRNCSOCOPNDB-AOKDLOFSSA-N |
| Smiles | [H][C@](C)([C@](O)=O)/C=C/C=[C@@](C)\[C@H]1CN[C@H]([C@@](O)=O)[C@H]1CC(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Domoic acid
参考文献 for Domoic acid
参考文献是支持产品生物活性的出版物。
Agrawal and Evans (1986) The primary afferent depolarizing action of kainate in the rat. Br.J.Pharmacol. 87 345 PMID: 3513882
Debonnel et al (1989) Domoic acid, the alleged 'mussel toxin', might produce its neurotoxic effect through kainate receptor activation: an electro-physiological study in rat dorsal hippocampus. Can.J.Physiol.Pharmacol. 67 29 PMID: 2540893
Watkins et al (1990) Experiments with kainate and quisqualate agonists and antagonists in relation to the sub-classification of 'non-NMDA' receptors. Excitatory Amino Acids and Synaptic Plasticity. Ed 49
Hampson and Manalo (1998) The activation of glutamate receptors by kainic acid and domoic acid. Nat.Toxins 6 153 PMID: 10223631
按产品操作查看相关产品
关键词: Domoic acid, Domoic acid supplier, Potent, selective, kainate, agonists, Glutamate, Kainate, Receptors, iGluR, Ionotropic, 0269, Tocris Bioscience
1 篇 Domoic acid 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Domoic acid 的部分引用包括：
Rojas et al (2013) Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Mol Pharmacol 83 106 PMID: 23066089
Domoic acid 的评论
目前没有该产品的评论。 Be the first to review Domoic acid and earn rewards!
Have you used Domoic acid?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.