Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewDPPE fumarate
说明： Inhibitor of histamine binding at the intracellular binding site
化学名： N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine fumarate
生物活性 for DPPE fumarate
Binds with high affinity to the antiestrogen binding site but not to the estrogen receptor. Induces of sterol accumulation in MCF7 cells. An inhibitor of histamine binding at the intracellular histamine (Hlc) site.
技术数据 for DPPE fumarate
| 分子量 | 399.49 |
| 公式 | C19H25NO.C4H4O4 |
| 储存 | Desiccate at -20°C |
| CAS Number | 1185241-83-1 |
| PubChem ID | 45073473 |
| InChI Key | ZOOMDYHTGZSGDD-WLHGVMLRSA-N |
| Smiles | [H]OC(=O)\C=C\C(=O)O[H].CCN(CC)CCOC1=CC=C(CC2=CC=CC=C2)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for DPPE fumarate
分析证书目前不在网上提供。
请联系客户服务
请联系客户服务
参考文献 for DPPE fumarate
参考文献是支持产品生物活性的出版物。
Brandes et al (1990) Histamine as an intracellular messenger. Biochem.Pharmacol. 40 1677 PMID: 2242003
Brandes and Hermonat (1984) A diphenylmethane derivative specific for the antiestrogen binding site found in rat liver microsomes. Biochem.Biophys.Res.Commun. 123 724 PMID: 6548377
Sturman et al (1994) Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice. Agents Actions 41 C68 PMID: 7976808
Kedjouar et al (2004) Molecular characterization of the microsomal tamox. binding site. J.Biol.Chem. 279 34048 PMID: 15175332
按产品操作查看相关产品
关键词: DPPE fumarate, DPPE fumarate supplier, Ligand, antiestrogen, binding, site, inhibitors, inhibits, histamine, intracellular, ER, ERR, Estrogen, Receptors, Histaminergic-, Compounds, Histaminergic-Related, and, Related, 0743, Tocris Bioscience
1 篇 DPPE fumarate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 DPPE fumarate 的部分引用包括：
Dolma et al (2016) Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell 29 859 PMID: 27300435
DPPE fumarate 的评论
目前没有该产品的评论。 Be the first to review DPPE fumarate and earn rewards!
Have you used DPPE fumarate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Histamine Receptors Scientific Review
Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.