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Discontinued Product
1009 has been discontinued.
View all Glutamate (Metabotropic) Group I Receptors products.
说明： Group I and II mGlu antagonist
化学名： (RS)-α-Ethyl-4-carboxyphenylglycine
纯度： ≥99% (HPLC)
生物活性 for E4CPG
Novel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG (Cat. No. 0336).
技术数据 for E4CPG
| 分子量 | 223.23 |
| 公式 | C11H13NO4 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 170846-89-6 |
| PubChem ID | 3937355 |
| InChI Key | AIEFWRHRHFRLFT-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)(CC)C1=CC=C(C(O)=O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for E4CPG
参考文献 for E4CPG
参考文献是支持产品生物活性的出版物。
Bedingfield et al (1995) Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). Br.J.Pharmacol. 116 3323 PMID: 8719814
Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745
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关键词: E4CPG, E4CPG supplier, Group, II, group, I, mGlur, antagonists, Receptors, mGlu2, mGlu3, mGluR2, mGluR3, Glutamate, Metabotropic, mGlu1, mGlu5, mGluR1, mGluR5, (Metabotropic), 1009, Tocris Bioscience
2 篇 E4CPG 的引用文献
引用文献是使用了 Tocris 产品的出版物。 E4CPG 的部分引用包括：
Balakrishnan et al (2009) Slow glycinergic transmission mediated by transmitter pooling. Nat Neurosci 12 286 PMID: 19198604
Newman (2005) Calcium increases in retinal glial cells evoked by light-induced neuronal activity. Neuropharmacology 25 5502 PMID: 15944378
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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