Endothelin 2 (human)

Cat. No. 1164 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： ET_A/ET_B agonist

别名： ET-2

纯度： ≥95% (HPLC)

引用文献 (2)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Endothelin 2 (human)

Endothelin 2 (human) is an endogenous peptide found predominately in the kidney and intestine. Displays similar selectivity for ET_A and ET_B endothelin receptors.

技术数据 for Endothelin 2 (human)

分子量	2547
公式	C₁₁₅H₁₆₀O₃₂N₂₆S₄
序列	CSCSSWLDKECVYFCHLDIIW (Modifications: Disulfide bridges: 1-15, 3-11)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	123562-20-9
PubChem ID	16133808
InChI Key	MLFJHYIHIKEBTQ-IYRKOGFYSA-N
Smiles	[H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC3=C1C=CC=C3)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Endothelin 2 (human)

溶解性	Soluble to 1 mg/ml in DMSO

产品说明书 for Endothelin 2 (human)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Endothelin 2 (human)

参考文献是支持产品生物活性的出版物。

Inoue et al (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc.Natl.Acad.Sci.U.S.A. 86 2863 PMID: 2649896

Servitja et al (1998) Involvement of ET_A and ET_B receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes. Br.J.Pharmacol. 124 1728 PMID: 9756390

Yanagisawa and Masaski (1989) Molecular biology and biochemistry of the endothelins. TiPS 10 374 PMID: 2690429

If you know of a relevant reference for Endothelin 2 (human), please let us know.

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关键词: Endothelin 2 (human), Endothelin 2 (human) supplier, ETA/ETB, agonist, Endothelin, Non-Selective, ET, Receptors, Endothelin2, (human), ET-2, Non-selective, 1164, Tocris Bioscience

2 篇 Endothelin 2 (human) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Endothelin 2 (human) 的部分引用包括：

Im et al (2019) INN inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A. Nat Commun 10 1387 PMID: 30918259

Khan et al (2006) Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon. Br J Pharmacol 147 607 PMID: 16432510

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