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Submit ReviewEndothelin 3 (human, rat) is an endogenous neuropeptide and potent vasoconstrictor. Displays selectivity for the putative ETC endothelin receptor.
分子量 | 2643 |
公式 | C121H168N26O33S4 |
序列 |
CTCFTYKDKECVYYCHLDIIW (Modifications: Disulfide bridges: 1-15, 3-11) |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 117399-93-6 |
PubChem ID | 16133809 |
InChI Key | OQGZWNZGVYLIFX-JQWUVQPESA-N |
Smiles | [H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@@H](NC1=O)[C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
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溶解性 | Soluble to 1 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Inoue et al (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc.Natl.Acad.Sci.U.S.A. 86 2863 PMID: 2649896
Servitja et al (1998) Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes. Br.J.Pharmacol. 124 1728 PMID: 9756390
Yanagisawa and Masaski (1989) Molecular biology and biochemistry of the endothelins. TiPS 10 374 PMID: 2690429
If you know of a relevant reference for Endothelin 3 (human, rat), please let us know.
关键词: Endothelin 3 (human, rat), Endothelin 3 (human, rat) supplier, Potent, vasoconstrictor, Endothelin, Non-Selective, ET, Receptors, agonists, ETB, Endothelin3, (human, rat), ET-3, Non-selective, 1162, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Endothelin 3 (human, rat) 的部分引用包括:
Khan et al (2006) Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon. Br J Pharmacol 147 607 PMID: 16432510
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