Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewExo1
说明： Inhibits Golgi-ER traffic; blocks exocytosis
化学名： 2-[(4-Fluorobenzoyl)amino]-benzoic acid methyl ester
纯度： ≥99% (HPLC)
生物活性 for Exo1
Exo1 is a reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC50 ~ 20 μM). Has similar, but not identical, action to brefeldin A (Cat. No. 1231).
技术数据 for Exo1
| 分子量 | 273.26 |
| 公式 | C15H12FNO3 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 461681-88-9 |
| PubChem ID | 310557 |
| InChI Key | KIAPWMKFHIKQOZ-UHFFFAOYSA-N |
| Smiles | COC(=O)C1=CC=CC=C1NC(=O)C1=CC=C(F)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Exo1
参考文献 for Exo1
参考文献是支持产品生物活性的出版物。
Feng et al (2003) Exo1: A new chemical inhibitor of the exocytic pathway. Proc.Natl.Acad.Sci.U.S.A. 100 6469 PMID: 12738886
按标靶查看相关产品
关键词: Exo1, Exo1 supplier, inhibitors, inhibits, Golgi-ER, traffic, blocks, exocytosis, Golgi, ADP-ribosylation, factor, ARF1, GTPase, Exocytosis, 1850, Tocris Bioscience
2 篇 Exo1 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Exo1 的部分引用包括：
Greene et al (2017) XE991 and Linopirdine are state-dependent inhibitors for Kv7/KCNQ channels that favor activated single subunits. J.Pharmacol.Exp.Ther. 362 177 PMID: 28483800
Eppler et al (2017) Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion. PLoS One 12 e0172443 PMID: 28273099
Exo1 的评论
目前没有该产品的评论。 Be the first to review Exo1 and earn rewards!
Have you used Exo1?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image