FERb 033

Name: FERb 033
Brand: Tocris Bioscience
SKU: 3523

Cat. No. 3523 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3523 has been discontinued.

View all Estrogen and Related Receptors products.

说明： Potent and selective ERβ agonist

化学名： 2-Chloro-3'-fluoro-3,4'-dihydroxy-[1,1-biphenyl]-4-carboxaldehyde oxime

纯度： ≥98% (HPLC)

说明书

引用文献

通路 (1)

生物活性技术数据说明书参考文献

生物活性 for FERb 033

FERb 033 is a potent and selective ERβ receptor agonist (K_i = 7.1 nM, EC₅₀ = 4.8 nM). Displays 62-fold selectivity over ERα.

技术数据 for FERb 033

分子量	281.67
公式	C₁₃H₉ClFNO₃
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	1111084-78-6
PubChem ID	74429219
InChI Key	IEBJACOMZQEPOY-UHFFFAOYSA-N
Smiles	OC1=C(/C=N/O)C=CC(C2=CC=C(O)C(F)=C2)=C1Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for FERb 033

分析证书/产品说明书

化学品安全技术说明书

参考文献 for FERb 033

参考文献是支持产品生物活性的出版物。

Minutolo et al (2009) Structural evolutions of salicylaldoximes as selective agonists for estrogen receptor β. J.Med.Chem. 52 858 PMID: 19128016

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Estrogen and Related Receptors

关键词: FERb 033, FERb 033 supplier, FERb033, estrogen, ERbeta, ERb, ERβ, receptors, agonists, oestrogen, Estrogen, and, Related, Receptors, 3523, Tocris Bioscience

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Pathways for FERb 033

Estrogen Signaling Pathway

Estrogen is a steroid hormone that is responsible for the regulation of growth, differentiation and function of the reproductive system. Estrogen signaling is often dysregulated in breast cancer and osteoporosis.