Fluorobexarotene

Name: Fluorobexarotene
Brand: Tocris Bioscience
SKU: 4064

Cat. No. 4064 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4064 has been discontinued.

View all Retinoid X Receptors products.

说明： RXR agonist

化学名： 2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid

纯度： ≥97% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Fluorobexarotene

Fluorobexarotene is a RXR agonist (K_i = 12 nM; EC₅₀ = 43 nM at RXRα receptors). Displays similar RAR agonist activity to bexarotene; exhibits an apparent RXR binding affinity 75% greater than bexarotene.

许可信息

Manufactured and sold under license from Arizona State University - Patent Pending

技术数据 for Fluorobexarotene

分子量	366.47
公式	C₂₄H₂₇FO₂
储存	Store at +4°C
纯度	≥97% (HPLC)
CAS Number	1190848-23-7
PubChem ID	25195496
InChI Key	LWKAWHRSPCHMPJ-UHFFFAOYSA-N
Smiles	CC(C(C(C3=CC=C(C(O)=O)C(F)=C3)=C)=C2)=CC1=C2C(C)(C)CCC(C)1C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Fluorobexarotene

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Fluorobexarotene

参考文献是支持产品生物活性的出版物。

Wagner et al (2009) Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene). J.Med.Chem. 52 5950 PMID: 19791803

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篇 Fluorobexarotene 的引用文献

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目前没有 Fluorobexarotene 的引用文献。