G-Protein antagonist peptide

Name: G-Protein antagonist peptide
Brand: Tocris Bioscience
SKU: 1931

Cat. No. 1931 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1931 has been discontinued.

View all Heterotrimeric G-protein GTPases products.

说明： Inhibits G protein activation by GPCRs

别名： GPAnt-2

说明书

引用文献 (2)

生物活性技术数据说明书参考文献

生物活性 for G-Protein antagonist peptide

G-Protein antagonist peptide is a substance P-related peptide that inhibits binding of G proteins to their receptors. Competitively and reversibly inhibits M₂ muscarinic receptor activation of G_i or G_o and inhibits G_s activation by β-adrenoceptors.

技术数据 for G-Protein antagonist peptide

分子量	1093.27
公式	C₅₇H₆₄N₁₂O₉S
序列	XQWFWWM (Modifications: X = Glp, Trp-3 = Trp-5 = Trp-6 = D-Trp, Met-7 = C-terminal amide)
储存	Desiccate at -20°C
CAS Number	143675-79-0
PubChem ID	71308571
InChI Key	WSYRBHQWMXTCHQ-SFIKJRKMSA-N
Smiles	[H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for G-Protein antagonist peptide

分析证书/产品说明书

化学品安全技术说明书

参考文献 for G-Protein antagonist peptide

参考文献是支持产品生物活性的出版物。

Mukai et al (1992) G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J.Biol.Chem. 267 16237 PMID: 1379592

按标靶查看相关产品

关键词: G-Protein Antagonist peptide, G-Protein Antagonist peptide supplier, inhibitors, inhibits, G, protein, activation, by, GPCRs, Gi, Go, Gs, G-Protein, Heterotrimeric, antagonists, GPAnt2, substance, P, GPAnt-2, G-protein, GTPases, 1931, Tocris Bioscience

2 篇 G-Protein antagonist peptide 的引用文献

引用文献是使用了 Tocris 产品的出版物。 G-Protein antagonist peptide 的部分引用包括：

Nogueras-Ortiz (2017) Retromer stops beta-arrestin 1 mediated signaling from internalized cannabinoid 2 receptors. Mol Biol Cell 28 3554 PMID: 28954865

Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888