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Submit ReviewGBLD 345
说明： High affinity benzodiazepine agonist
化学名： 2-(4-Aminophenyl)-3-methoxy-6-(3-methoxyphenyl)-methylimidazo[1,2-b]pyridazine
生物活性 for GBLD 345
A high affinity benzodiazepine agonist (IC50 against diazepam = 1 nM).
技术数据 for GBLD 345
| 分子量 | 375.43 |
| 公式 | C21H21N5O2 |
| 储存 | Store at RT |
| CAS Number | 122479-08-7 |
| Smiles | NC(C=C4)=CC=C4C2=C(OC)N(C(C=C3)=N2)N=C3NCC1=CC=CC(OC)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for GBLD 345
分析证书目前不在网上提供。
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参考文献 for GBLD 345
参考文献是支持产品生物活性的出版物。
Davies et al (1992) Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors. Biochem.Pharmacol. 44 1555 PMID: 1358075
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关键词: GBLD 345, GBLD 345 supplier, High, affinity, benzodiazepine, agonists, GABAA, Receptors, GBLD345, 0770, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
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The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.