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Submit ReviewGLP-1 (7-37) is a endogenous GLP-1 receptor ligand; bioactive and truncated form of GLP-1; insulinotropic hormone.
分子量 | 3355.71 |
公式 | C151H228N40O47 |
序列 | HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 106612-94-6 |
PubChem ID | 16133830 |
InChI Key | GCYXWQUSHADNBF-AAEALURTSA-N |
Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
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溶解性 | Soluble to 1 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Marchetti et al (2012) A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets. Diabetologia 55 3262 PMID: 22965295
Ban et al (2010) Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor. Endocrinology 151 1520 PMID: 20172966
If you know of a relevant reference for GLP-1 (7-37), please let us know.
关键词: GLP-1 (7-37), GLP-1 (7-37) supplier, Endogenous, GLP-1, receptor, ligands, bioactive, truncated, form, Glucagon, like, peptide, insulinotropic, proglucagon, agonists, Glucagon-Like, Peptide, 1, Receptors, 5374, Tocris Bioscience
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.