GLP-2 (3-33)

Cat. No. 7725 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Peptide antagonist of glucagon-like peptide-2 (GLP-2) receptor

纯度： ≥95% (HPLC)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for GLP-2 (3-33)

GLP-2(3-33) is a peptide antagonist of glucagon-like peptide-2 (GLP-2) receptor. In cells, GLP-2(3-33) is generated by cleaving off the two N-terminal amino acids of GLP-2 with dipeptidylpeptidase IV (DPPIV). In high-fat diet (HFD) fed mice, GLP-2(3-33) treatment results in increased dyslipidemia and hepatic lipid accumulation. Chronic treatment of GLP-2(3-33) in HFD fed mice can cause hyperglycemia, glucose intolerance, high plasma insulin level after glucose load, increased pancreas weight and β-cell expansion.

技术数据 for GLP-2 (3-33)

分子量	3557.93
公式	C₁₅₆H₂₄₂N₄₀O₅₃S
序列	DGSFSDEMNTILDNLAARDFINWLIQTKITD
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	275801-62-2
PubChem ID	71455345
InChI Key	MYKFSDGCGNRIEA-KXTJMAPWSA-N
Smiles	O=C(NCC(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for GLP-2 (3-33)

溶解性	Soluble to 2 mg/ml in 0.01M PBS

产品说明书 for GLP-2 (3-33)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for GLP-2 (3-33)

参考文献是支持产品生物活性的出版物。

Baldassano et al (2015) GLP-2 involvement as a beneficial factor in the glucose homeostasis in mice fed a high fat diet. J.Cell Physiol. 230 3029 PMID: 25967277

Baldassano et al (2016) Influence of endogenous glucagon-like peptide-2 on lipid disorders in mice fed a high-fat diet. Endocr.Res. 41 317 PMID: 26906293

If you know of a relevant reference for GLP-2 (3-33), please let us know.

按标靶查看相关产品

关键词: GLP-2 (3-33), GLP-2 (3-33) supplier, GLP2(3-33), peptide, antagonist, glucagon-like, peptide-2, GLP-2, receptor, lipid, disorders, Glucose, Homeostasis, Glucagon-Like, Peptide, 2, Receptors, 7725, Tocris Bioscience

篇 GLP-2 (3-33) 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 GLP-2 (3-33) 的引用文献。您是否知道使用了 Tocris GLP-2 (3-33) 的优秀论文？请告知我们.

GLP-2 (3-33) 的评论

目前没有该产品的评论。 Be the first to review GLP-2 (3-33) and earn rewards!

Have you used GLP-2 (3-33)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.