Golgicide A

Name: Golgicide A
Brand: Tocris Bioscience
SKU: 3584

Cat. No. 3584 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3584 has been discontinued.

View all Arf GTPases products.

说明： Potent, selective and reversible inhibitor of GBF1 ArfGEF

化学名： 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

纯度： ≥98% (HPLC)

说明书

引用文献 (5)

生物活性技术数据说明书参考文献

生物活性 for Golgicide A

Golgicide A is a potent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo. Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans-Golgi network.

技术数据 for Golgicide A

分子量	284.3
公式	C₁₇H₁₄F₂N₂
储存	Store at RT
纯度	≥98% (HPLC)
CAS Number	1139889-93-2
PubChem ID	25113626
InChI Key	NJZHEQOUHLZCOX-FTLRAWMYSA-N
Smiles	FC4=CC([C@]3([H])[C@]([H])2CC=C3)=C(C(F)=C4)NC2C1=CN=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Golgicide A

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Golgicide A

参考文献是支持产品生物活性的出版物。

Saenz et al (2008) Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nature Chem.Biol. 5 157

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