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Submit ReviewGuanabenz acetate
说明： α2 agonist. Also I2 selective ligand
化学名： [(2,6-Dichlorobenzylidene)amino]guanidine acetate
纯度： ≥98% (HPLC)
生物活性 for Guanabenz acetate
Guanabenz acetate is a α2-adrenergic agonist and IGRS (imidazoline I2 binding site) selective ligand.
技术数据 for Guanabenz acetate
| 分子量 | 291.14 |
| 公式 | C8H8Cl2N4.CH3CO2H |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 23256-50-0 |
| PubChem ID | 5702062 |
| InChI Key | MCSPBPXATWBACD-GAYQJXMFSA-N |
| Smiles | CC(O)=O.ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Guanabenz acetate
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| DMSO | 21.84 | 75 |
制备储备液 for Guanabenz acetate
以下数据基于产品分子量 291.14。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.75 mM | 4.58 mL | 22.9 mL | 45.8 mL |
| 3.75 mM | 0.92 mL | 4.58 mL | 9.16 mL |
| 7.5 mM | 0.46 mL | 2.29 mL | 4.58 mL |
| 37.5 mM | 0.09 mL | 0.46 mL | 0.92 mL |
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产品说明书 for Guanabenz acetate
参考文献 for Guanabenz acetate
参考文献是支持产品生物活性的出版物。
Evans and Anderson (1995) Renal effects of infusion of rilmenidine and guan. in conscious dogs: contribution of peripheral and central nervous system α2-adrenoceptors. Br.J.Pharmacol. 116 1557 PMID: 8564219
Holmes et al (1983) Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. Drugs 26 212 PMID: 6352237
Michel and Insel (1989) Are there multiple imidazoline binding sites? Trends Pharmacol.Sci. 10 342 PMID: 2690423
Merck Index 12 4585
If you know of a relevant reference for Guanabenz acetate, please let us know.
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关键词: Guanabenz acetate, Guanabenz acetate supplier, α2-adrenoceptor, alpha2-adrenoceptor, α2-Adrenergic, alpha2-Adrenergic, a2-adrenoceptor, a2-adrenergic, agonists, I2, selective, ligands, Adrenoceptors, Imidazoline, Adrenergic, Alpha-2, Receptors, 0885, Tocris Bioscience
5 篇 Guanabenz acetate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Guanabenz acetate 的部分引用包括：
Ye et al (2013) Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome. J Korean Med Sci 110 141 PMID: 23248313
Nevin et al (2017) Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes. Am J Hum Genet 100 617 PMID: 28366443
Wan et al (2014) Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flow. PLoS One 9 e105699 PMID: 25157407
Hamamura et al (2015) Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis. Proc Natl Acad Sci U S A 4 84 PMID: 25977571
Cardin and Schmidt (2004) Noradrenergic inputs mediate state dependence of auditory responses in the avian song system. Bone Joint Res 24 7745 PMID: 15342742
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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