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GYY 4137 morpholine salt

Cat. No. 3658 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Slow-releasing H2S donor
化学名： P-(4-Methoxyphenyl)-P-4-morpholinylphosphinodithioic acid morpholine salt
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for GYY 4137 morpholine salt

GYY 4137 morpholine salt is a slow-releasing H2S donor. Exhibits vasodilator and antihypertensive activity. Activity causes slow dilation of blood vessels in vitro and in vivo; does not influence vascular smooth muscle cell viability in culture. Water-soluble.

技术数据 for GYY 4137 morpholine salt

分子量 376.47
公式 C11H16NO2PS2.C4H9NO
储存 Store at -20°C
CAS Number 106740-09-4
PubChem ID 46937261
InChI Key YZMHNNLDUWRZFW-UHFFFAOYSA-N
Smiles S=P(N1CCOCC1)(C2=CC=C(OC)C=C2)S.N3CCOCC3

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for GYY 4137 morpholine salt

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 37.65 100

制备储备液 for GYY 4137 morpholine salt

以下数据基于产品分子量 376.47。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.66 mL 13.28 mL 26.56 mL
5 mM 0.53 mL 2.66 mL 5.31 mL
10 mM 0.27 mL 1.33 mL 2.66 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

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产品说明书 for GYY 4137 morpholine salt

分析证书/产品说明书
化学品安全技术说明书

参考文献 for GYY 4137 morpholine salt

参考文献是支持产品生物活性的出版物。

Li et al (2008) Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137). Circulation 117 2351 PMID: 18443240

Whiteman et al (2010) The effect of hydrogen sulfide donors on lipopolysaccaride-induced formation of inflammatory mediators in macrophages. Antioxid.Redox.Signal. 12 1147 PMID: 19769459

Lee et al (2011) The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo. PLoS One 6 e21077 PMID: 21701688

Liu et al (2013) Hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E-/- mice. Br.J.Pharmacol. [Epub ahead of print] PMID: 23713790

If you know of a relevant reference for GYY 4137 morpholine salt, please let us know.

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关键词: GYY 4137 morpholine salt, GYY 4137 morpholine salt supplier, GYY4137, morpholine, h2s, hydrogen, sulfide, sulphide, donors, slow, releasing, release, vasodilator, antihypertensives, Miscellaneous, Compounds, 3658, Tocris Bioscience

1 篇 GYY 4137 morpholine salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 GYY 4137 morpholine salt 的部分引用包括：

Y S et al (2020) Hydrogen sulfide, oxygen, and calcium regulation in developing human airway smooth muscle. FASEB J 34 12991-13004 PMID: 32777143

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