GYY 4137 morpholine salt

Name: GYY 4137 morpholine salt
Brand: Tocris Bioscience
SKU: 3658

Cat. No. 3658 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3658 has been discontinued.

View all Miscellaneous Compounds products.

说明： Slow-releasing H₂S donor

化学名： P-(4-Methoxyphenyl)-P-4-morpholinylphosphinodithioic acid morpholine salt

说明书

引用文献 (1)

生物活性技术数据说明书参考文献

生物活性 for GYY 4137 morpholine salt

GYY 4137 morpholine salt is a slow-releasing H₂S donor. Exhibits vasodilator and antihypertensive activity. Activity causes slow dilation of blood vessels in vitro and in vivo; does not influence vascular smooth muscle cell viability in culture. Water-soluble.

技术数据 for GYY 4137 morpholine salt

分子量	376.47
公式	C₁₁H₁₆NO₂PS₂.C₄H₉NO
储存	Store at -20°C
CAS Number	106740-09-4
PubChem ID	46937261
InChI Key	YZMHNNLDUWRZFW-UHFFFAOYSA-N
Smiles	S=P(N1CCOCC1)(C2=CC=C(OC)C=C2)S.N3CCOCC3

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for GYY 4137 morpholine salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for GYY 4137 morpholine salt

参考文献是支持产品生物活性的出版物。

Li et al (2008) Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137). Circulation 117 2351 PMID: 18443240

Whiteman et al (2010) The effect of hydrogen sulfide donors on lipopolysaccaride-induced formation of inflammatory mediators in macrophages. Antioxid.Redox.Signal. 12 1147 PMID: 19769459

Lee et al (2011) The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo. PLoS One 6 e21077 PMID: 21701688

Liu et al (2013) Hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E^-/- mice. Br.J.Pharmacol. [Epub ahead of print] PMID: 23713790

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Miscellaneous Compounds

关键词: GYY 4137 morpholine salt, GYY 4137 morpholine salt supplier, GYY4137, morpholine, h2s, hydrogen, sulfide, sulphide, donors, slow, releasing, release, vasodilator, antihypertensives, Miscellaneous, Compounds, 3658, Tocris Bioscience

1 篇 GYY 4137 morpholine salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 GYY 4137 morpholine salt 的部分引用包括：

Y S et al (2020) Hydrogen sulfide, oxygen, and calcium regulation in developing human airway smooth muscle. FASEB J 34 12991-13004 PMID: 32777143