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HM 50316

Cat. No. 5850 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5850 has been discontinued.

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说明： High affinity FABP4 inhibitor
化学名： 2-[[2'-[1-(4-Chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]oxy]-2-methylpropanoic acid
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for HM 50316

HM 50316 is a high affinity FABP4 inhibitor (Ki < 1 nM). Highly selective for FABP4 over FABP3. Inhibits LPS-induced activation of murine macrophages in vitro.

技术数据 for HM 50316

分子量 515.02
公式 C29H23ClN2O3S
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 1310361-52-4
PubChem ID 49872404
InChI Key HOACFVYJBHHSBC-UHFFFAOYSA-N
Smiles CC(OC1=CC=CC(C2=C(C3=NN(C4=CC=C(C=C4)Cl)C(C5=CC=CS5)=C3)C=CC=C2)=C1)(C(O)=O)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for HM 50316

参考文献是支持产品生物活性的出版物。

Liu et al (2011) New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein. Bioorg.Med.Chem.Lett. 21 2949 PMID: 21481589

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关键词: HM 50316, HM 50316 supplier, HM50316, fatty, acid-binding, protein, adipocyte, a-FABP, FABP4, inhibitors, inhibits, high, affinity, Fatty, Acid, Binding, Proteins, 5850, Tocris Bioscience

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