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Submit ReviewHX 630
说明： RXR synergist
化学名： 4-(7,8,9,10-Tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl-benzoic acid
纯度： ≥98% (HPLC)
生物活性 for HX 630
HX 630 is a RXR agonist. Acts as a retinoid synergist; enhances the potency of AM 80 (Cat. No. 3507) in a HL-60 cell differentiation assay.
许可信息
Sold under licence.
技术数据 for HX 630
| 分子量 | 441.58 |
| 公式 | C28H27NO2S |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 188844-52-2 |
| PubChem ID | 9889522 |
| InChI Key | PFGCWQPTOKPRRK-UHFFFAOYSA-N |
| Smiles | CC3(C)CCC(C)(C)C(C3=C4)=CC2=C4C(C5=CC=C(C(O)=O)C=C5)=NC1=CC=CC=C1S2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for HX 630
参考文献 for HX 630
参考文献是支持产品生物活性的出版物。
Umemiya et al (1997) Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers. J.Med.Chem. 40 4222 PMID: 9435893
Ohashi et al (2002) Effect of natural and synthetic retinoids on the proliferation and differentiation of three canine melanoma cell lines. J.Vet.Med.Sci. 64 169 PMID: 11913557
Ishida et al (2003) Clinically potential subclasses of retinoid synergists revealed by gene expression profiling. Mol.Cancer Ther. 2 49 PMID: 12533672
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关键词: HX 630, HX 630 supplier, HX630, synergists, retinoids, retinoic, pan-RXR, agonists, retinoid, synergist, Retinoid, X, Receptor, 3913, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Retinoid Receptors Scientific Review
Written by Alexander Moise, this review summarizes the nature of retinoid receptors, their isotype and isoform variants and modulation of retinoid signaling. Compounds available from Tocris are listed.