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Submit ReviewIbotenic acid
说明： NMDA agonist; also non selective mGlu agonist
化学名： α-Amino-(3-hydroxy-5-isoxazolyl)acetic acid
纯度： ≥98% (HPLC)
生物活性 for Ibotenic acid
Ibotenic acid is a NMDA and metabotropic glutamate receptor agonist.
技术数据 for Ibotenic acid
| 分子量 | 158.11 |
| 公式 | C5H6N2O4 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 2552-55-8 |
| PubChem ID | 1233 |
| InChI Key | IRJCBFDCFXCWGO-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)C1=CC(O)=NO1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Ibotenic acid
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 1.58 | 10 | |
| 1.1eq. NaOH | 15.81 | 100 |
制备储备液 for Ibotenic acid
以下数据基于产品分子量 158.11。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.32 mL | 31.62 mL | 63.25 mL |
| 5 mM | 1.26 mL | 6.32 mL | 12.65 mL |
| 10 mM | 0.63 mL | 3.16 mL | 6.32 mL |
| 50 mM | 0.13 mL | 0.63 mL | 1.26 mL |
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产品说明书 for Ibotenic acid
参考文献 for Ibotenic acid
参考文献是支持产品生物活性的出版物。
Johnston et al (1968) Central actions of ibotenic acid and muscimol. Biochem.Pharmacol. 17 2488 PMID: 5752907
Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597 PMID: 1329206
Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 1 PMID: 7623957
Watkins and Evans (1981) Excitatory amino acid transmitters. Annu.Rev.Pharmacol.Toxicol. 21 165 PMID: 6112965
If you know of a relevant reference for Ibotenic acid, please let us know.
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关键词: Ibotenic acid, Ibotenic acid supplier, Non-Selective, NMDA, agonists, mGlur, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Metabotropic, Non-selective, mGlu, 0285, Tocris Bioscience
4 篇 Ibotenic acid 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Ibotenic acid 的部分引用包括：
Joseph et al (2018) Role of Prefrontal Cortex Anti- and Pro-inflammatory Cytokines in the Development of Abnormal Behaviors Induced by Disconnection of the Ventral Hippocampus in Neonate Rats. Front Behav Neurosci 12 244 PMID: 30459571
Karlsson et al (2013) Exaggerated cue-induced reinstatement of cocaine seeking but not incubation of cocaine craving in a developmental rat model of schizophrenia. Psychopharmacology (Berl) 226 45 PMID: 23010798
Pitts and Takahashi (2011) The central amygdala nucleus via corticotropin-releasing factor is necessary for time-limited consolidation processing but not storage of contextual fear memory. Neuroreport 95 86 PMID: 21093597
Renouard et al (2015) The supramammillary nucleus and the claustrum activate the cortex during REM sleep. Neurobiol Learn Mem 1 e1400177 PMID: 26601158
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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