ICI 162,846

Name: ICI 162,846
Brand: Tocris Bioscience
SKU: 0833

Cat. No. 0833 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0833 has been discontinued.

View all Histamine H<sub>2</sub> Receptors products.

说明： Potent H₂ antagonist, active in vivo

化学名： N-[1-(4-Carboxamidobutyl)-1H-pyrazol-3-yl)]-N'-(2,2,2-trifluoroethyl)guanidine

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for ICI 162,846

ICI 162,846 is a potent histamine H₂ receptor antagonist.

许可信息

Sold with the permission of AstraZeneca UK Ltd.

技术数据 for ICI 162,846

分子量	306.29
公式	C₁₁H₁₇F₃N₆O
储存	Store at RT
CAS Number	84545-30-2
PubChem ID	134778
InChI Key	ALCSGJCIESECFD-UHFFFAOYSA-N
Smiles	NC(=O)CCCCN1C=CC(=N1)\N=C(/N)NCC(F)(F)F

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for ICI 162,846

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化学品安全技术说明书

参考文献 for ICI 162,846

参考文献是支持产品生物活性的出版物。

Gompertz et al (1991) Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model. Agents Actions 33 161 PMID: 1716826

Streett et al (1988) Morphological stomach findings in rats and mice treated with the H₂ receptor antagonists, ICI 125,211 and ICI 162,846. Toxicol.Pathol. 16 299 PMID: 2903545

Wilson et al (1986) Inhibition of human gastric secretion by ICI 162,846 - a new histamine H₂ receptor antagonist. Br.J.Clin.Pharmacol. 21 685 PMID: 2874823

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关键词: ICI 162,846, ICI 162,846 supplier, Potent, H2, antagonists, active, vivo, Receptors, Histamine, histaminergic, ICI162846, AstraZeneca, 0833, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Histamine Receptors Scientific Review

Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.