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Submit ReviewICI 89406
Discontinued Product
0832 has been discontinued.
View all Non-selective Adrenergic β Receptors products.
说明： β antagonist
化学名： N-[2-[3-(2-Cyanophenoxy)-2-hydroxypropylamino]ethyl]-N'-phenylurea
纯度： ≥99% (HPLC)
生物活性 for ICI 89406
β-adrenergic antagonist and low efficacy partial agonist; does not affect resting cardiac parameters.
许可信息
Sold with the permission of AstraZeneca UK Ltd.
技术数据 for ICI 89406
| 分子量 | 354.41 |
| 公式 | C19H22N4O3 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 53671-71-9 |
| PubChem ID | 123686 |
| InChI Key | HTLWRKRZKFAAAH-UHFFFAOYSA-N |
| Smiles | OC(CNCCNC(=O)NC1=CC=CC=C1)COC1=C(C=CC=C1)C#N |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for ICI 89406
参考文献 for ICI 89406
参考文献是支持产品生物活性的出版物。
Mai (1990) β-Adrenergic Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch. 3 187
关键词: ICI 89406, ICI 89406 supplier, β-adrenoceptor, beta-adrenoceptor, b-adrenoceptor, β-adrenergic, beta-adrenergic, b-adrenergic, antagonists, Receptors, Non-Selective, ICI89406, AstraZeneca, Non-selective, Adrenergic, Beta, 0832, Tocris Bioscience
2 篇 ICI 89406 的引用文献
引用文献是使用了 Tocris 产品的出版物。 ICI 89406 的部分引用包括：
Mistry et al (2013) Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. J Med Chem 56 3852 PMID: 23614528
Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther 329 350 PMID: 19144685
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.