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Submit ReviewImiloxan hydrochloride
说明： Highly selective α2B antagonist
别名： RS 21361
化学名： 2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxan hydrochloride
纯度： ≥98% (HPLC)
生物活性 for Imiloxan hydrochloride
Imiloxan hydrochloride is a moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity.
许可信息
Sold with the permission of Roche Bioscience
技术数据 for Imiloxan hydrochloride
| 分子量 | 280.75 |
| 公式 | C14H16N2O2.HCl |
| 储存 | Desiccate at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 81167-22-8 |
| PubChem ID | 172975 |
| InChI Key | ANDJPJNFVJXEKX-UHFFFAOYSA-N |
| Smiles | Cl.CCN1C=CN=C1CC1COC2=CC=CC=C2O1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Imiloxan hydrochloride
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 28.07 | 100 |
制备储备液 for Imiloxan hydrochloride
以下数据基于产品分子量 280.75。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.56 mL | 17.81 mL | 35.62 mL |
| 5 mM | 0.71 mL | 3.56 mL | 7.12 mL |
| 10 mM | 0.36 mL | 1.78 mL | 3.56 mL |
| 50 mM | 0.07 mL | 0.36 mL | 0.71 mL |
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产品说明书 for Imiloxan hydrochloride
参考文献 for Imiloxan hydrochloride
参考文献是支持产品生物活性的出版物。
Michel et al (1990) Assessment of imiloxan as a selective α2B-adrenoceptor antagonist. Br.J.Pharmacol. 99 560 PMID: 1970500
Michel and Whiting (1981) 2-(2-Imidazolylmethyl)-1,4-benzodioxans, a series of selective alpha2-adrenoceptor antagonists. Br.J.Pharmacol. 74 255P
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关键词: Imiloxan hydrochloride, Imiloxan hydrochloride supplier, selective, α2B-adrenoceptor, alpha2B-adrenoceptor, antagonists, α2b-adrenergic, alpha2b-adrenergic, a2-adrenoceptor, a2-adrenergic, Receptors, RS21361, RS, 21361, Adrenergic, Alpha-2, 0986, Tocris Bioscience
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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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