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Submit ReviewIPAG is a potent σ-receptor antagonist.
分子量 | 395.29 |
公式 | C17H22IN3 |
储存 | Store at RT |
纯度 | ≥98% (HPLC) |
CAS Number | 193527-91-2 |
PubChem ID | 4239764 |
InChI Key | UUKPIWYXWLJPJF-UHFFFAOYSA-N |
Smiles | IC1=CC=C(NC(=N)NC2C3CC4CC(C3)CC2C4)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Whittemore et al (1997) Antagonism of N-MthD.-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326 PMID: 9223571
Wilson et al (1991) Radiosynthesis of σ receptor ligands for positron emission tomography: 11C- and 18F-labelled guanidines. J.Med.Chem. 34 1867 PMID: 1648140
关键词: IPAG, IPAG supplier, Potent, σ, sigma, antagonists, General, Receptors, Sigma-Related, 0544, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 IPAG 的部分引用包括:
Kim et al (2012) Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression. Biochem Biophys Res Commun 426 177 PMID: 22925888
Brimson et al (2011) Antagonists show GTP-sensitive high-affinity binding to the sigma-1 receptor. Br J Pharmacol 164 772 PMID: 21486275
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