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Submit ReviewETB endothelin receptor antagonist.
分子量 | 1410 |
公式 | C68H92N14O15S2 |
序列 |
CVYFCHLDIIW (Modifications: Disulfide bridge between 1 - 5) |
储存 | Desiccate at -20°C |
CAS Number | 144602-02-8 |
PubChem ID | 16142511 |
InChI Key | OETKRDJJNWJFOP-PJLZVMSOSA-N |
Smiles | [H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@@H](NC1=O)C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Haynes et al (1993) Endothelin; progress in pharmacology and physiology. TiPS 14 225 PMID: 8372400
Karaki et al (1993) ETB receptor antagonist, IRL 1038, selectively inhibits the endothelin-induced endothelium-dependent vascular relaxation. Eur.J.Pharmacol. 231 371 PMID: 8449230
关键词: IRL-1038, IRL-1038 supplier, ETB, antagonists, Receptors, Endothelin, 1195, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 IRL-1038 的部分引用包括:
Khan et al (2006) Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon. Br J Pharmacol 147 607 PMID: 16432510
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