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Submit ReviewJIP-1 (153-163)
说明： JNK-selective inhibitor peptide
别名： TI-JIP
生物活性 for JIP-1 (153-163)
Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.
技术数据 for JIP-1 (153-163)
| 分子量 | 1341.6 |
| 公式 | C61H104N20O14 |
| 序列 |
RPKRPTTLNLF (Modifications: Phe-11 = C-terminal amide) |
| 储存 | Desiccate at -20°C |
| CAS Number | 438567-88-5 |
| PubChem ID | 90479803 |
| InChI Key | BWQKOFMNXWAKES-QHYOMBHZSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for JIP-1 (153-163)
参考文献 for JIP-1 (153-163)
参考文献是支持产品生物活性的出版物。
Barr et al (2002) Identification of the critical features of a small peptide inhibitor of JNK activity. J.Biol.Chem. 277 10987 PMID: 11790767
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关键词: JIP-1 (153-163), JIP-1 (153-163) supplier, JNK-selective, inhibitors, inhibits, peptide, c-Jun, N-Terminal, Kinase, SAPKs, Stress-Activated, Protein, MAPK, Mitogen-Activated, protein, TIJIP, TI-JIP, JNK/c-jun, 1565, Tocris Bioscience
1 篇 JIP-1 (153-163) 的引用文献
引用文献是使用了 Tocris 产品的出版物。 JIP-1 (153-163) 的部分引用包括：
Kumar et al (2015) The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma. Springerplus 4 19 PMID: 25625039
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
MAPK Signaling Scientific Review
MAP kinase signaling is integral to the regulation of numerous cellular processes such as proliferation and differentiation, and as a result is an important focus of cancer and immunology research. Updated for 2016, this review discusses the regulation of the MAPK pathway and properties of MAPK cascades. Compounds available from Tocris are listed.
Pathways for JIP-1 (153-163)
