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KLH 45

Cat. No. 5865 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5865 has been discontinued.

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说明： Potent DDHD2 inhibitor
化学名： N-Cyclohexyl-N-(2-phenylethyl)-4-[4-(trifluoromethoxy)phenyl]-2H-1,2,3-triazole-2-carboxamide
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for KLH 45

KLH 45 is a potent DDHD2 inhibitor (IC50 = 1.3 nM). Selective for DDHD2 over 40 other serine hydrolases, but does exhibit cross-reactivity with ABHD6. Active in vivo. Increases brain triacylglycerol levels in mice.

许可信息

Sold under license from The Scripps Research Institute

技术数据 for KLH 45

分子量 458.48
公式 C24H25F3N4O2
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1632236-44-2
PubChem ID 126970670
InChI Key FYOYNRLSBYWAHL-UHFFFAOYSA-N
Smiles O=C(N(C1CCCCC1)CCC2=CC=CC=C2)N(N=C3)N=C3C(C=C4)=CC=C4OC(F)(F)F

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for KLH 45

参考文献是支持产品生物活性的出版物。

Inloes et al (2014) The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase. Proc.Natl.Acad.Sci.U.S.A. 111 14924 PMID: 25267624

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关键词: KLH 45, KLH 45 supplier, KLH45, DDHD2, inhibits, inhibitors, potent, in, vivo, active, serine, hydrolase, Other, Hydrolases, 5865, Tocris Bioscience

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