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Submit ReviewL-BMAA hydrochloride
说明： Neurotoxic amino acid
化学名： 3-(Methylamino)-L-alanine hydrochloride
生物活性 for L-BMAA hydrochloride
L-BMAA hydrochloride is a neurotoxic glutamate agonist originally isolated from Cycas circinalis. Implicated in the pathogenesis of amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam (Guam ALS-PD).
技术数据 for L-BMAA hydrochloride
| 分子量 | 154.6 |
| 公式 | C4H10N2O2.HCl |
| 储存 | Store at -20°C |
| CAS Number | 16012-55-8 |
| PubChem ID | 51358333 |
| InChI Key | VDXYGASOGLSIDM-DFWYDOINSA-N |
| Smiles | N[C@@H](CNC)C(O)=O.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for L-BMAA hydrochloride
参考文献 for L-BMAA hydrochloride
参考文献是支持产品生物活性的出版物。
Weiss et al (1989) Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons. Brain Res. 497 64 PMID: 2551452
Vega et al (1968) The preparation of L- and D-α-amino-β<-methylaminopropionic acids and the identification of the compound isolated from Cycas circinalis as the L-isomer. Phytochemistry 7 1885
关键词: L-BMAA hydrochloride, L-BMAA hydrochloride supplier, Neurotoxic, amino, acid, Glutamate, mGlur, Receptors, Metabotropic, iGluR, Ionotropic, Miscellaneous, 2538, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.