L-Kynurenine

Discontinued Product

4393 has been discontinued.

View all Aryl Hydrocarbon Receptors products.
说明: Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand
化学名: L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
纯度: ≥98% (HPLC)
说明书
引用文献 (1)
评论 (1)

生物活性 for L-Kynurenine

L-Kynurenine is a tryptophan catabolite; endogenous activator of the aryl hydrocarbon receptor (AhR). Immunosuppressant; suppresses allogeneic T cell proliferation.

技术数据 for L-Kynurenine

分子量 208.21
公式 C10H12N2O3
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 2922-83-0
PubChem ID 161166
InChI Key YGPSJZOEDVAXAB-QMMMGPOBSA-N
Smiles O=C(C[C@H](N)C(O)=O)C1=C(N)C=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for L-Kynurenine

分析证书/产品说明书
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参考文献 for L-Kynurenine

参考文献是支持产品生物活性的出版物。

Opitz et al (2011) An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478 197 PMID: 21976023

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关键词: L-Kynurenine, L-Kynurenine supplier, Kynurenine, tryptophan, catabolite, aryl, hydrocarbon, receptor, ligand, endogenous, AHR, ligands, tryptophan-2,3-dioxygenase, TDO, Kyn, Aryl, Hydrocarbon, Receptors, Tryptophan, 2,3, dioxygenase, 4393, Tocris Bioscience

1 篇 L-Kynurenine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 L-Kynurenine 的部分引用包括:

Bassel F et al (2020) Correlation Patterns Among B7 Family Ligands and Tryptophan Degrading Enzymes in Hepatocellular Carcinoma. Front Oncol 10 1632 PMID: 33014820


L-Kynurenine 的评论

平均评分: 5 (Based on 1 Review.)

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IDO assay standard (L-Kynurenine).
By Debanjan Mukhopadhyay on 01/11/2018
分析类型: Ex Vivo
种属: Human
细胞系/组织: Human foreskin fibroblast

I use this product as a standard for Indoleamine 2,3 dioxygenase assay. This product worked excellent as a standard for Tryptophan catabolism assay.

This product is very pure and you can use it from a range of 5 uM to 1500 uM.