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Submit ReviewL-NIL hydrochloride
说明： Selective iNOS inhibitor
化学名： N6-(1-Iminoethyl)-L-lysine hydrochloride
生物活性 for L-NIL hydrochloride
L-NIL hydrochloride is a selective inhibitor of inducible nitric oxide synthase (IC50 = 3.3 μM).
技术数据 for L-NIL hydrochloride
| 分子量 | 223.7 |
| 公式 | C8H17N3O2.HCl |
| 储存 | Desiccate at -20°C |
| CAS Number | 150403-89-7 |
| PubChem ID | 9794509 |
| InChI Key | HJYWSATZDBEAOS-FJXQXJEOSA-N |
| Smiles | N=C(NCCCC[C@@H](C(O)=O)N)C.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for L-NIL hydrochloride
参考文献 for L-NIL hydrochloride
参考文献是支持产品生物活性的出版物。
Connor et al (1995) Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur.J.Pharmacol. 273 15 PMID: 7537678
Moore et al (1994) L-N6-(1-Iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J.Med.Chem. 37 3886 PMID: 7525961
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关键词: L-NIL hydrochloride, L-NIL hydrochloride supplier, Selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, 1139, Tocris Bioscience
4 篇 L-NIL hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 L-NIL hydrochloride 的部分引用包括：
Pais et al (2008) Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. Mar Drugs 5 43 PMID: 18844999
Elks et al (2013) Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism. PLoS Pathog 9 e1003789 PMID: 24367256
Hervera et al (2011) Peripheral effects of mor. and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling. Mol Pain 7 25 PMID: 21486477
Hervera et al (2010) The role of nitric oxide in the local antiallodynic and antihyperalgesic effects and expression of delta-opioid and cannabinoid-2 receptors during neuropathic pain in mice. J Pharmacol Exp Ther 334 887 PMID: 20498253
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