L-NIO dihydrochloride

Cat. No. 0546 8 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： NOS inhibitor

化学名： N⁵-(1-Iminoethyl)-L-ornithine dihydrochloride

引用文献 (8)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for L-NIO dihydrochloride

L-NIO dihydrochloride is an Inhibitor of nitric oxide (NO) synthase. Inhibits iNOS, eNOS and nNOS. Active in vivo.

技术数据 for L-NIO dihydrochloride

分子量	246.13
公式	C₇H₁₅N₃O₂.2HCl
储存	Desiccate at -20°C
CAS Number	159190-44-0
PubChem ID	2733507
InChI Key	RYCMAAFECCXGHI-ILKKLZGPSA-N
Smiles	N[C@H](C(O)=O)CCCNC(C)=N.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for L-NIO dihydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	24.61	100

制备储备液 for L-NIO dihydrochloride

以下数据基于产品分子量 246.13。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	4.06 mL	20.31 mL	40.63 mL
5 mM	0.81 mL	4.06 mL	8.13 mL
10 mM	0.41 mL	2.03 mL	4.06 mL
50 mM	0.08 mL	0.41 mL	0.81 mL

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产品说明书 for L-NIO dihydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for L-NIO dihydrochloride

参考文献是支持产品生物活性的出版物。

Moncada et al (1997) XIV. International Union of Pharmacology nomenclature in nitric oxide research. Pharmacol.Rev. 49 137 PMID: 9228663

Mulligan et al (1992) Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis. Br.J.Pharmacol. 107 1159 PMID: 1281719

Rees et al (1990) Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br.J.Pharmacol. 101 746 PMID: 1706208

If you know of a relevant reference for L-NIO dihydrochloride, please let us know.

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关键词: L-NIO dihydrochloride, L-NIO dihydrochloride supplier, Potent, eNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Endothelial, Synthase, NO, Synthases, iNOS, nNOS, 0546, Tocris Bioscience