L-NMMA acetate

Cat. No. 0771 6 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Non-selective NOS inhibitor

化学名： NG-Monomethyl-L-arginine acetate

引用文献 (6)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for L-NMMA acetate

L-NMMA acetate is a competitive, irreversible inhibitor of all three NOS isoforms.

技术数据 for L-NMMA acetate

分子量	248.28
公式	C₇H₁₆N₄O₂.CH₃CO₂H
储存	Desiccate at RT
CAS Number	53308-83-1
PubChem ID	135242
InChI Key	IKPNWIGTWUZCKM-JEDNCBNOSA-N
Smiles	CC(O)=O.N=C(NCCC[C@H](N)C(O)=O)NC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for L-NMMA acetate

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	12.41	50

制备储备液 for L-NMMA acetate

以下数据基于产品分子量 248.28。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.5 mM	8.06 mL	40.28 mL	80.55 mL
2.5 mM	1.61 mL	8.06 mL	16.11 mL
5 mM	0.81 mL	4.03 mL	8.06 mL
25 mM	0.16 mL	0.81 mL	1.61 mL

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产品说明书 for L-NMMA acetate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for L-NMMA acetate

参考文献是支持产品生物活性的出版物。

Olken et al (1991) Inactivation of macrophage nitric oxide synthase activity by N(G)-methyl-L-arginine. Biochem.Biophys.Res.Commun. 177 828 PMID: 2049105

Rees et al (1990) Characterisation of three inhibitors of endothelial nitric oxide synthase in vivo and in vitro. Br.J.Pharmacol. 101 746 PMID: 1706208

Reif and McCreedy et al (1995) N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a differential pattern of inactivation toward the three nitric oxide synthases. Arch.Biochem.Biophys. 320 170 PMID: 7540822

Saksuma et al (1988) Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc.Natl.Acad.Sci.U.S.A. 85 8664 PMID: 3263652

If you know of a relevant reference for L-NMMA acetate, please let us know.

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关键词: L-NMMA acetate, L-NMMA acetate supplier, Non-Selective, NOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, NO, Synthases, nNOS, iNOS, eNOS, Non-selective, 0771, Tocris Bioscience