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Submit ReviewLEP (116-130) (mouse)
说明： Synthetic leptin peptide fragment
生物活性 for LEP (116-130) (mouse)
LEP (116-130) (mouse) is a synthetic leptin peptide fragment. Restricts weight gain and reduces food intake in female mice lacking endogenously circulating active leptin.
技术数据 for LEP (116-130) (mouse)
| 分子量 | 1560.73 |
| 公式 | C64H109N19O24S |
| 序列 |
SCSLPQTSGLQKPES (Modifications: Ser-15 = C-terminal amide) |
| 储存 | Desiccate at -20°C |
| CAS Number | 258276-95-8 |
| PubChem ID | 90471193 |
| InChI Key | YEHDWBRMEXDYLT-RDEOYNLOSA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for LEP (116-130) (mouse)
参考文献 for LEP (116-130) (mouse)
参考文献是支持产品生物活性的出版物。
Grasso et al (1997) In vivo effects of leptin-related synthetic peptides on body weight and food intake in female ob/ob mice: localization of leptin activity to domains between amino acid residues 106-140. Endocrinology 138 1413 PMID: 9075696
Grasso et al (1999) Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor. Diabetes 48 2204 PMID: 10535455
Rozhavskaya et al (2000) Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis and thermoregulation. Endocrinology 141 2501 PMID: 10875251
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关键词: LEP (116-130) (mouse), LEP (116-130) (mouse) supplier, Synthetic, leptin, peptide, fragment, Receptors, adipokines, Leptin, 2985, Tocris Bioscience
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