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Submit Review[Leu5]-Enkephalin
说明： Endogenous opioid agonist peptide
别名： ICI 114740,Dynorphin-(1-5),YGGFL
纯度： ≥95% (HPLC)
生物活性 for [Leu5]-Enkephalin
[Leu5]-Enkephalin is an endogenous opioid agonist peptide; inhibits electrically stimulated contractions in mouse vas deferens (IC50 = 11.4 nM). Short-acting in vivo.
技术数据 for [Leu5]-Enkephalin
| 分子量 | 555.63 |
| 公式 | C28H37N5O7 |
| 序列 | YGGFL |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 58822-25-6 |
| PubChem ID | 461776 |
| InChI Key | URLZCHNOLZSCCA-VABKMULXSA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for [Leu5]-Enkephalin
| 溶解性 | Soluble to 1 mg/ml in water |
产品说明书 for [Leu5]-Enkephalin
参考文献 for [Leu5]-Enkephalin
参考文献是支持产品生物活性的出版物。
DiMaio et al (1982) Synthesis and pharmacological characterization in vitro of cyclic enkephalin analogues: effect of conformational constraints on opiate receptor selectivity. J.Med.Chem. 25 1432 PMID: 6296388
Law and Loh (1978) 3H-Leu5-enkephalin specific binding to synaptic membrane - comparison with 3H-dihydromorphine and 3H-naloxone. Res.Commun.Chem.Pathol.Pharmacol. 21 409 PMID: 705021
Meunier et al (1977) Binding of Leu5-enkephalin and Met5-enkephalin to a particulate fraction from rat cerebrum. FEBS Lett. 77 209 PMID: 862920
If you know of a relevant reference for [Leu5]-Enkephalin, please let us know.
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关键词: [Leu5]-Enkephalin, [Leu5]-Enkephalin supplier, Endogenous, opioids, agonists, peptide, Receptors, ICI114740, enkephalin, ICI, 114740, Dynorphin-(1-5), YGGFL, Miscellaneous/Non-selective, Opioids, 1889, Tocris Bioscience
1 篇 [Leu5]-Enkephalin 的引用文献
引用文献是使用了 Tocris 产品的出版物。 [Leu5]-Enkephalin 的部分引用包括：
Markkanen and Petäjä-Repo (2008) N-glycan-mediated quality control in the endoplasmic reticulum is required for the expression of correctly folded delta-opioid receptors at the cell surface. J Biol Chem 283 29086 PMID: 18703511
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