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Submit ReviewEndogenous bradykinin receptor agonist that displays some selectivity for the B2 receptor (Ki values are 2.54 and 0.63 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. Twice as potent as bradykinin (Cat No. 3004) in vivo.
分子量 | 1188.39 |
公式 | C56H85N17O12 |
序列 | KRPPGFSPFR |
储存 | Desiccate at -20°C |
CAS Number | 342-10-9 |
PubChem ID | 5311111 |
InChI Key | FYSKZKQBTVLYEQ-FSLKYBNLSA-N |
Smiles | [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Regoli and Barabe (1980) Pharmacology of bradykinin and related kinins. Pharmacol.Rev. 32 1 PMID: 7015371
Regoli et al (2001) Classification of kinin receptors. Biol.Chem. 382 31 PMID: 11258668
Leeb-Lundberg et al (2005) International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27 PMID: 15734727
关键词: Lys-Bradykinin, Lys-Bradykinin supplier, Potent, bradykinin, receptor, agonists, B2, B1, Receptors, Kallidin, Bradykinin, 3227, Tocris Bioscience
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