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Submit ReviewMAIT 203 is an inhibits interaction of APC and Asef (RhoGEF4). Inhibits colorectal cancer cell migration and invasion in vitro.
分子量 | 2517.83 |
公式 | C106H177N43O29 |
序列 |
AGEAXYEGGGGGRKKRRQRRR (Modifications: Ala-1 = Z-Ala, X-5= 3-Cyclopentyl-L-alanine, Arg-21= C-terminal amide) |
储存 | Store at -20°C |
PubChem ID | 132470912 |
InChI Key | BWXFXXHBUFJJSA-YLOXEXSPSA-N |
Smiles | C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Jiang et al (2017) Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat.Chem.Biol. 13 994 PMID: 28759015
关键词: MAIT 203, MAIT 203 supplier, MAIT203, APC, Asef, interaction, inhibitors, inhibits, colorectal, cancer, migration, Rho, 6382, Tocris Bioscience
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