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View all Heterotrimeric G-protein GTPases products.Mastoparan is a peptide activator of Gi and Go.
分子量 | 1479 |
公式 | C70H131N19O15 |
序列 |
INLKALAALAKKIL (Modifications: Leu-14 = C-terminal amide) |
储存 | Desiccate at -20°C |
CAS Number | 72093-21-1 |
PubChem ID | 6324633 |
InChI Key | MASXKPLGZRMBJF-MVSGICTGSA-N |
Smiles | [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Higashijima and Ros (1991) Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go. J.Biol.Chem. 266 12655 PMID: 1905730
Longland et al (1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan. J.Biol.Chem. 274 14799 PMID: 10329678
Mousli et al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358 PMID: 2122563
Raynor et al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753 PMID: 1847132
关键词: Mastoparan, Mastoparan supplier, Activator, Gi, Go, Gi/o, G-Protein, Signaling, Signalling, Heterotrimeric, G-protein, GTPases, 1192, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Mastoparan 的部分引用包括:
Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888
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