MCOPPB trihydrochloride

Name: MCOPPB trihydrochloride
Brand: Tocris Bioscience
SKU: 3763

Cat. No. 3763 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3763 has been discontinued.

View all NOP Receptors products.

说明： Potent NOP receptor agonist

化学名： 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole trihydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for MCOPPB trihydrochloride

MCOPPB trihydrochloride is a high affinity NOP receptor agonist (pK_i = 10.07 for the human NOP receptor). Exhibits anxiolytic effects with no effect on memory or locomotion. Regarded as one of the most potent, non-peptide NOP full agonists in vitro.

许可信息

Sold for research purposes under agreement from Pfizer Inc.

技术数据 for MCOPPB trihydrochloride

分子量	534.05
公式	C₂₆H₄₀N₄.3HCl
储存	Store at -20°C
纯度	≥99% (HPLC)
CAS Number	1108147-88-1
PubChem ID	25208093
InChI Key	DTIPEVOPCGEULQ-RFCADEKQSA-N
Smiles	CC5(CCCCCCC5)N(CC4)CCC4N2C1=CC=CC=C1N=[C@@]2[C@H]3CNCCC3.Cl.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for MCOPPB trihydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for MCOPPB trihydrochloride

参考文献是支持产品生物活性的出版物。

Hirao et al (2008) Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent. J.Pharmacol.Sci. 106 361 PMID: 18319566

Hayashi et al (2009) Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain f J.Med.Chem. 52 610 PMID: 19125610

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篇 MCOPPB trihydrochloride 的引用文献

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