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Submit ReviewMephenytoin
说明： CYP2C19 substrate. Anticonvulsant
化学名： (±)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
纯度： ≥98% (HPLC)
生物活性 for Mephenytoin
Mephenytoin is a CYP2C19 and CYP2B6 substrate. Anticonvulsant.
技术数据 for Mephenytoin
| 分子量 | 218.25 |
| 公式 | C12H14N2O2 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 50-12-4 |
| PubChem ID | 4060 |
| InChI Key | GMHKMTDVRCWUDX-UHFFFAOYSA-N |
| Smiles | O=C1C(C2=CC=CC=C2)(CC)NC(N1C)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Mephenytoin
参考文献 for Mephenytoin
参考文献是支持产品生物活性的出版物。
Knabe and Wunn (1980) Racemic and optically active hydantoins from disubstituted cyanoacetic acids. Arch.Pharmacol. 313 53
Foti et al (2008) CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles. Drug Meta. Dispos. 36 523 PMID: 18048485
Tamminga et al (2001) Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse events. Br.J.Clin.Pharmacol. 51 471 PMID: 11422005
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关键词: Mephenytoin, Mephenytoin supplier, CYP2C19, Anticonvulsant, Cytochrome, P450, 3276, Tocris Bioscience
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