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Submit Review(-)-5'-DMH-CBD
说明： Metabolically stable anandamide transport inhibitor
别名： (-)-5'-Dimethylheptyl-cannabidiol
化学名： 5-(1,1-Dimethylheptyl)-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol
生物活性 for (-)-5'-DMH-CBD
(-)-5'-DMH-CBD is an anandamide membrane transport inhibitor (IC50 = 14 μM) that is relatively metabolically stable. Displays some affinity for CB2 receptors but has only weak affinity for CB1 receptors and has no activity at VR1 receptors or FAAH. Anticonvulsive in vivo following systemic administration.
技术数据 for (-)-5'-DMH-CBD
| 分子量 | 370.57 |
| 公式 | C25H38O2 |
| 储存 | Desiccate at -20°C |
| CAS Number | 97452-63-6 |
| PubChem ID | 126670 |
| InChI Key | MPJURNPNPDQYSY-LEWJYISDSA-N |
| Smiles | C=[C@](C)[C@@H]1CCC(C)=C[C@H]1[C@]2=C(O)C=C(C(C)(C)CCCCCC)C=C2O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for (-)-5'-DMH-CBD
参考文献 for (-)-5'-DMH-CBD
参考文献是支持产品生物活性的出版物。
Bisogno et al (2001) Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br.J.Pharmacol. 134 845 PMID: 11606325
Leite et al (1982) Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. Pharmacology 24 141 PMID: 7071126
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关键词: (-)-5'-DMH-CBD, (-)-5'-DMH-CBD supplier, Metabolically, stable, anandamide, transporters, inhibitors, inhibits, AMT, Anandamide, Cannabinoids, Monoamine, Neurotransmitter, (-)-5-DMH-CBD, cannabidiol, (-)-5'-Dimethylheptyl-cannabidiol, Cannabinoid, Transporters, 1481, Tocris Bioscience
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