Mito-HE

Pricing Availability   Qty
说明: Red-fluorescent mitochondrial superoxide indicator. Used for: live cell imaging. Application: confocal microscopy, flow cytometry
化学名: [6-(3,8-Diamino-6-phenyl-5(6H)-phenanthridinyl)hexyl]triphenylphosphonium iodide
纯度: ≥80% (HPLC)
说明书
引用文献
评论
文献 (1)

生物活性 for Mito-HE

Key information: Mito-HE is a red fluorescent mitochondrial superoxide indicator in live cells.

Used for: live cell imaging, mitochondrial superoxide detection in Parkinson's and Alzheimer's disease in vitro models.

Application: confocal imaging, flow cytometry.

Properties and Photophysical Data: Selective for mitochondrial superoxides over other reactive oxygen and nitrogen species. Excitation and emission maxima (λ) are 510 nm and 580 nm, respectively; extinction coefficient = 117,000 M-1cm-1.

It is recommended to prepare stock solutions in DMSO.

Optical Data for Mito-HE

Mito-HE Dye Spectra
Emission Color Red
λabs 510 nm
λem 580 nm
Extinction Coefficient (ε) 11700 M-1cm-1
Cell Permeable Yes
Application Confocal Imaging, Flow Cytometry

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

技术数据 for Mito-HE

分子量 759.72
公式 C43H43IN3P
储存 Store at -20°C
纯度 ≥80% (HPLC)
CAS Number 1003197-00-9
PubChem ID 160231797
InChI Key NMKOJFMSKHLXRV-UHFFFAOYSA-M
Smiles NC1=CC=C2C(C(C3=CC=CC=C3)N(C4=CC(N)=CC=C24)CCCCCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)=C1.[I-]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Mito-HE

参考文献是支持产品生物活性的出版物。

Rhee et al (2020) Modeling secondary iron overload cardiomyopathy with human induced pluripotent stem cell-derived cardiomyocytes. Cell Rep. 32 107886 PMID: 32668256

Renaudin et al (2021) BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance. Cell Rep. 36 109478 PMID: 34348152

Mukhopadhyay et al (2007) Simple quantitative detection of mitochondrial superoxide production in live cells. Biochem.Biophys.Res.Commun. 358 203 PMID: 17475217

Mukhopadhyay et al (2007) Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy. Nat.Protoc. 2 2295 PMID: 17853886

Robinson et al (2006) Selective fluorescent imaging of superoxide in vivo using ethidium-based probes. Proc.Natl.Acad.Sci.U.S.A. 103 15038 PMID: 17015830

Chen et al (2020) Trilobatin protects against Aβ 25-35-induced hippocampal HT22 cells apoptosis through mediating ROS/p38/caspase 3-dependent pathway. Front.Pharmacol. 11 584 PMID: 32508629

Chung et al (2016) Parkin and PINK1 patient iPSC-derived midbrain dopamine neurons exhibit mitochondrial dysfunction and α-synuclein accumulation. Stem Cell Rep. 7 664 PMID: 27641647


If you know of a relevant reference for Mito-HE, please let us know.

关键词: Mito-HE, Mito-HE supplier, MitoHE, red, mitochondrial, marker, stain, mitotracker, mitochondria, MitoSOX, MitoSox, superoxide, indicator, Fluorescent, Cell, Indicators, and, Sensors, Other, Mitochondria, Dyes, Probes, 7641, Tocris Bioscience

篇 Mito-HE 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Mito-HE 的引用文献。 您是否知道使用了 Tocris Mito-HE 的优秀论文? 请告知我们.

Mito-HE 的评论

目前没有该产品的评论。 Be the first to review Mito-HE and earn rewards!

Have you used Mito-HE?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。


Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals