ML 352 hydrochloride

Name: ML 352 hydrochloride
Brand: Tocris Bioscience
SKU: 5725

Cat. No. 5725 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5725 has been discontinued.

View all Acetylcholine Transporters products.

说明： High affinity and selective presynaptic choline transporter (CHT) inhibitor

化学名： 4-Methoxy-N-[[3-(1-methylethyl)-5-isoxazolyl]methyl]-3-[(1-methyl-4-piperidinyl)oxy]benzamide hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for ML 352 hydrochloride

High affinity and selective presynaptic choline transporter (CHT) inhibitor (K_i = 92 nM). Exhibits selectivity for CHT over dopamine, serotonin and noradrenalin transporters; acetylcholinesterase and cholineacetyltransferase; and a panel of 65 other GPCRs, ion channels and transporters.

技术数据 for ML 352 hydrochloride

分子量	423.93
公式	C₂₁H₂₉N₃O₄.HCl
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	1962928-20-6
PubChem ID	121513888
InChI Key	UKLCTDBUTADGBD-UHFFFAOYSA-N
Smiles	COC1=CC=C(C(NCC3=CC(C(C)C)=NO3)=O)C=C1OC2CCN(C)CC2.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for ML 352 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for ML 352 hydrochloride

参考文献是支持产品生物活性的出版物。

Ennis et al (2015) Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporter. ACS Chem.Neurosci. 6 417 PMID: 25560927

Bollinger et al (2015) Synthesis and structure-activity relationships of a series of 4-methoxy-3-(piperidin-4-yl)oxy benzamides as novel inhibitors of the presynaptic choline transporter. Bioorg.Med.Chem.Lett. 25 1757 PMID: 25801932

按标靶查看相关产品

关键词: ML 352 hydrochloride, ML 352 hydrochloride supplier, ML352, hydrochloride, 1649450-12-3, high, affinity, selective, presynaptic, choline, transporter, CHT, Acetylcholine, Transporters, 5725, Tocris Bioscience

篇 ML 352 hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 ML 352 hydrochloride 的引用文献。