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Submit ReviewMM 77 dihydrochloride
说明： 5-HT1A (postsynaptic) antagonist
化学名： 1-(2-Methoxyphenyl)-4-(4-succinimidobutyl)piperazine dihydrochloride
生物活性 for MM 77 dihydrochloride
MM 77 dihydrochloride is a highly potent and fairly selective 5-HT1A ligand, which may be a full antagonist at postsynaptic receptors.
技术数据 for MM 77 dihydrochloride
| 分子量 | 418.36 |
| 公式 | C19H27N3O3.2HCl |
| 储存 | Store at RT |
| CAS Number | 159187-70-9 |
| PubChem ID | 45073441 |
| InChI Key | ZYCVVOZXHNDRCO-UHFFFAOYSA-N |
| Smiles | Cl.Cl.COC1=CC=CC=C1N1CCN(CCCCN2C(=O)CCC2=O)CC1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for MM 77 dihydrochloride
参考文献 for MM 77 dihydrochloride
参考文献是支持产品生物活性的出版物。
Mokrosz et al (1994) 1-(2-Methoxyphenyl)-4-(4-succinimidobutyl)piperazine (MM 77): a new, potent, postsynaptic antagonist of 5-HT1A receptors. Med.Chem.Res. 4 161
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关键词: MM 77 dihydrochloride, MM 77 dihydrochloride supplier, 5-HT1A, postsynaptic, antagonists, Serotonin, Receptors, MM77, dihydrochloride, 0933, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.