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Submit ReviewMorphine hydrochloride is a narcotic opioid analgesic.
分子量 | 321.8 |
公式 | C17H19NO3.HCl |
储存 | Store at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 52-26-6 |
PubChem ID | 5464110 |
InChI Key | XCKKIKBIPZJUET-VYKNHSEDSA-N |
Smiles | O[C@@H]3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(C)CC4)[C@@]([H])2C=C3.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 16.09 | 50 |
以下数据基于产品分子量 321.8。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.5 mM | 6.22 mL | 31.08 mL | 62.15 mL |
2.5 mM | 1.24 mL | 6.22 mL | 12.43 mL |
5 mM | 0.62 mL | 3.11 mL | 6.22 mL |
25 mM | 0.12 mL | 0.62 mL | 1.24 mL |
参考文献是支持产品生物活性的出版物。
Merck Index 12 1074
If you know of a relevant reference for Morphine hydrochloride, please let us know.
关键词: Morphine hydrochloride, Morphine hydrochloride supplier, opioid, receptors, analgesic, Miscellaneous/Non-selective, Opioids, 5158, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Morphine hydrochloride 的部分引用包括:
Mohammad et al (2021) Effects of intrathecal and intracerebroventricular microinjection of kaempferol on pain: possible mechanisms of action. Res Pharm Sci 16 203-216 PMID: 34084207
Jose A et al (2021) An endogenous opioid circuit determines state-dependent reward consumption. Nature 598 646-651 PMID: 34646022
Prather et al (2013) CB1 and CB2 receptors are novel molecular targets for tamox. and 4OH-Tamoxifen. Biochem Biophys Res Commun 441 339 PMID: 24148245
Rajasekaran et al (2013) Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors. Toxicol Appl Pharmacol 269 100 PMID: 23537664
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Saline or morphine (10 mg/kg, s.c.) was injected 1 h prior to intrarectal instillation of peanut oil (Veh) or AITC 2% (v/v) in mice. Phosphorylation of p42/44 was analysed in spinal cord (Sc), thalamus (Th), hypothalamus (Hth), amygdala (Amy), and prefrontal cortex (Pfc) lysates using Western blot. Morphine significantly inhibited AITC-induced pp42/44 expression (shown in Image).
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.