Moxonidine hydrochloride

Name: Moxonidine hydrochloride
Brand: Tocris Bioscience
SKU: 2282

Cat. No. 2282 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2282 has been discontinued.

View all I<sub>1</sub> Receptors products.

说明： I₁ receptor and α₂-adrenoceptor agonist (I₁ > α₂)

化学名： 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Moxonidine hydrochloride

Mixed I₁ imidazoline receptor and α₂-adrenergic agonist; displays 40-fold higher affinity for I₁ receptors versus α₂-adrenoceptors. Centrally acting antihypertensive agent.

技术数据 for Moxonidine hydrochloride

分子量	278.14
公式	C₉H₁₂ClN₅O.HCl
储存	Desiccate at +4°C
纯度	≥98% (HPLC)
CAS Number	75536-04-8
PubChem ID	11231255
InChI Key	ZZPAWQYZQVUVHX-UHFFFAOYSA-N
Smiles	Cl.COC1=NC(C)=NC(Cl)=C1NC1=NCCN1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Moxonidine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Moxonidine hydrochloride

参考文献是支持产品生物活性的出版物。

Schafer et al (2002) Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and α₂-adrenoceptors. J.Pharmacol.Exp.Ther. 303 1163 PMID: 12438540

El-Ayoubi et al (2004) Imidazoline receptors but not a2-adrenoceptors are regulated in spontaneously hypertensive rat heart by chronic moxonidine treatment. J.Pharmacol.Exp.Ther. 310 446 PMID: 15075383

Chan et al (2005) Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clon. Neuroscience 132 991 PMID: 15857704

按标靶查看相关产品

按产品操作查看相关产品

查看全部 I₁ Receptor Agonists

关键词: Moxonidine hydrochloride, Moxonidine hydrochloride supplier, α2-adrenoceptor, alpha2-adrenoceptor, a2-adrenoceptor, α2-Adrenergic, alpha2-Adrenergic, a2-adrenergic, agonists, I1, receptors, Imidazoline, Receptors, Adrenergic, Alpha-2, 2282, Tocris Bioscience

篇 Moxonidine hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Moxonidine hydrochloride 的引用文献。