N-(3-Oxododecanoyl)-L-homoserine lactone

Discontinued Product

6548 has been discontinued.

View all Immunosuppressants products.
说明: Bacterial quorum sensing autoinducer; immunomodulator
化学名: 3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]dodecanamide
说明书
引用文献
评论

生物活性

N-(3-Oxododecanoyl)-L-homoserine lactone is a bacterial quorum sensing signal molecule. Inhibits lymphocyte proliferation and TNF-α and IL-12 production by LPS-stimulated macrophages. Inhibits or promotes antibody production at high and low concentrations, respectively, in keyhole limpet hemocyanin (KLH)-stimulated spleen cells. Immunomodulator.

技术数据

分子量 297.39
公式 C16H27NO4
储存 Store at -20°C
CAS Number 168982-69-2
PubChem ID 3246941
InChI Key PHSRRHGYXQCRPU-AWEZNQCLSA-N
Smiles CCCCCCCCCC(CC(N[C@H]1CCOC1=O)=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献

参考文献是支持产品生物活性的出版物。

Telford et al (1998) The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. Infect.Immun. 66 36 PMID: 9423836

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关键词: N-(3-Oxododecanoyl)-L-homoserine lactone, N-(3-Oxododecanoyl)-L-homoserine lactone supplier, OdDHL, quorum, sensing, sensors, autoinducers, Gram-negative, bacterial, Pseudomonas, aeruginosa, signaling, signalling, immunomodulator, Immunosuppressants, 6548, Tocris Bioscience

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