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Submit ReviewN-(3-Oxododecanoyl)-L-homoserine lactone is a bacterial quorum sensing signal molecule. Inhibits lymphocyte proliferation and TNF-α and IL-12 production by LPS-stimulated macrophages. Inhibits or promotes antibody production at high and low concentrations, respectively, in keyhole limpet hemocyanin (KLH)-stimulated spleen cells. Immunomodulator.
分子量 | 297.39 |
公式 | C16H27NO4 |
储存 | Store at -20°C |
CAS Number | 168982-69-2 |
PubChem ID | 3246941 |
InChI Key | PHSRRHGYXQCRPU-AWEZNQCLSA-N |
Smiles | CCCCCCCCCC(CC(N[C@H]1CCOC1=O)=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Telford et al (1998) The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. Infect.Immun. 66 36 PMID: 9423836
关键词: N-(3-Oxododecanoyl)-L-homoserine lactone, N-(3-Oxododecanoyl)-L-homoserine lactone supplier, OdDHL, quorum, sensing, sensors, autoinducers, Gram-negative, bacterial, Pseudomonas, aeruginosa, signaling, signalling, immunomodulator, Immunosuppressants, 6548, Tocris Bioscience
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